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Domain	Bioinformatics
Domain - extra
Year	2014
Starting	September 2014
Status	Closed
Subject	New homology based approaches for predicting the three-dimensional structure of RNA molecules.
Thesis advisor	DENISE Alain
Co-advisors
Laboratory	LRI Bioinfo
Collaborations
Abstract	Briefly, modeling RNA structures relies on two complementary approaches. The approach by homology is used when the structure of a sequence homologous to the sequence of interest has already been resolved experimentally. The main problem is to calculate an alignment between the known structure and the sequence. The ab initio approach is required when no homologous structure is known for the sequence of interest. It is also used, complementarily to the approach by homology, to predict the structure of parts of the sequence that does not correspond with the known structure. The present research project mainly focuses on comparative modeling and its combination with ab initio modeling.
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Expected funding	Research contract
Status of funding	Expected
Candidates
user	alain.denise
Created	Tuesday 18 of March, 2014 19:21:02 CET
LastModif	Tuesday 25 of March, 2014 13:13:13 CET

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Directrice
Nicole Bidoit
Assistante
Stéphanie Druetta
Conseiller aux thèses
Dominique Gouyou-Beauchamps

ED 427 - Université Paris-Sud
UFR Sciences Orsay
Bat 650 - aile nord - 417
Tel : 01 69 15 63 19
Fax : 01 69 15 63 87
courriel: ed-info at lri.fr